I think it all depends on the person.... Some people handle it better than others.
Perhaps one of the biggest things that is hard to take is the loss of family, friends, and your 'eco-system'. If you could actually call up a friend, bounce things off of them, discuss the possibilities without them going into 'zombie-mode' it would definitely be easier.
I mean, what if you had a group of five girlfriends, you all decided this was just getting a little weird, and left? You'd all be together, you'd still have things to do, people to talk to.... on and on.
But..... the Borg knows exactly what it is doing.... The same thing they put the Catholic Church down for in the past "excommunication", but the WT is even more extreme.
Blackmail, plain and simple.